Article

Arrhythmia variant associations and reclassifications in the eMERGE-III sequencing study

2021-04-06

Abstract excerpt

In 21,846 eMERGE-III participants, sequencing 10 arrhythmia syndrome disease genes identified 123 individuals with pathogenic or likely pathogenic (P/LP) variants. Compared to non-carriers, P/LP carriers had a significantly higher burden of arrhythmia phenotypes in their electronic health records (EHRs). Fifty one participants had variant results returned. Eighteen of these 51 participants had inherited arrhythmia...

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Literature Corpus work: bcd52345-ba01-57e1-acc7-61bdc22a2de2
DOI: 10.1101/2021.03.30.21254549

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