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Article

The frequency of gene variant reclassification and its impact on clinical management in the inherited arrhythmia clinic.

Heart rhythm - 1 Jun 2024

Young William J, Maung Soe, Ahmet Selda, Kirkby Claire, Ives Charlotte, Schilling Richard J, Lowe Martin, Lambiase Pier D

Abstract excerpt

BACKGROUND: Genetic testing in the inherited arrhythmia clinic informs risk stratification, clinical management, and family screening. Periodic review of variant classification is recommended as supporting evidence accrues over time. However, there is limited reporting of real-world data on the frequency and impact of variant reclassification. OBJECTIVE: The purpose of this study was to determine the burden of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38218330
DOI: 10.1016/j.hrthm.2024.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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