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Article

Clinical and genetic variant re-analysis among pediatric probands undergoing genetic testing for arrhythmia syndromes.

Heart rhythm - 1 Oct 2025

Stephens Sara B, Follansbee Christopher W, Novy Tyler, Howard Taylor S, Pham Tam Dan, Lang Anna M, Beecroft-Dawson Taylor, Yesso Abigail, Soludczyk Emily, Zou Wenxin, Fan Yuxin, Kim Jeffrey J, Valdes Santiago O, Miyake Christina Y

Abstract excerpt

BACKGROUND: Despite increases in genetic testing, longitudinal data regarding changes in diagnostic yield and variant reclassification for inherited arrhythmia syndromes are limited. OBJECTIVE: Determine longitudinal changes in diagnostic yield and variant classification. METHODS: Single-center retrospective study of probands <18 years undergoing genetic testing for suspected inherited cardiac conditions...

Read the complete abstract on PubMed

Topics

Humans
Genetic Testing
Male
Female
Retrospective Studies
Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Arrhythmias, Cardiac

Adolescent

Genetic Variation

Child, Preschool

DNA

Infant

Source

Identifiers

PMID: 40383177
DOI: 10.1016/j.hrthm.2025.05.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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