Article

Evolution of apoptotic signalling pathways within lophotrochozoans

2023-12-12

Abstract excerpt

Apoptosis is the main form of regulated cell death in metazoans. Apoptotic pathways are well characterised in nematode, fly and mammals, leading to a vision of the conservation of apoptotic pathways in metazoans. However, we recently showed that intrinsic apoptosis is in fact divergent among metazoans. In addition, extrinsic apoptosis is poorly studied in non-mammalian animals, making its evolution unclear. Conseq...

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Literature Corpus work: bcd12c69-9c35-523a-9e29-8c59535ac58d
DOI: 10.1101/2023.12.11.571055

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