Article

Untargeted metabolomics reveals sugar and homocysteine dysregulations in prodromal AD

2020-02-26

Abstract excerpt

<h4>Introduction</h4> Altered metabolism may occur early in Alzheimer’s disease (AD). We used untargeted high-resolution metabolomics in the cerebrospinal fluid (CSF) in mild cognitive impairment (MCI) to identify these alterations. <h4>Methods</h4> CSF from 92 normal controls and 93 MCI underwent untargeted metabolomics using high-resolution mass spectrometry with liquid chromatography. Partial least squares disc...

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Literature Corpus work: bc2ea12e-c083-5911-91fa-2b062cd73282
DOI: 10.1101/2020.02.23.20025064

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