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The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types

2024-06-24

Abstract excerpt

Matrigel remains the gold standard substrate for culture of induced pluripotent stem cells (iPSCs). However, its highly variable composition, animal origin and unpredictable effects on biological activity have been discussed for more than 3 decades. In this study, we explore the use of fragment E8 of recombinant laminin 511, commercially available in form of iMatrix-511, as an alternative to Matrigel for iPSC main...

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Literature Corpus work
bbe80700-9cc4-523d-b9df-05c4060ec1c6
DOI
10.1101/2024.06.20.599891
Open publication

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The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell typesDOI 10.1101/2024.06.20.599891
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