Article
The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types
2024-06-24
Abstract excerpt
Matrigel remains the gold standard substrate for culture of induced pluripotent stem cells (iPSCs). However, its highly variable composition, animal origin and unpredictable effects on biological activity have been discussed for more than 3 decades. In this study, we explore the use of fragment E8 of recombinant laminin 511, commercially available in form of iMatrix-511, as an alternative to Matrigel for iPSC main...
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Identifiers and source
- Literature Corpus work
- bbe80700-9cc4-523d-b9df-05c4060ec1c6
- DOI
- 10.1101/2024.06.20.599891
