Article

Predicting the Pathway Involvement of Compounds Annotated in the Reactome Knowledge-base

2024-11-11

Abstract excerpt

<h4>Motivation</h4> Pathway annotations of non-macromolecular (relatively small) biomolecules facilitate biological and biomedical interpretation of metabolomics datasets. However, low pathway annotation levels of detected biomolecules hinder this type of interpretation. Thus, predicting the pathway involvement of detected but unannotated biomolecules has high potential to improve metabolomics data analysis and o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bbdf80b6-c508-5b4b-825f-c76010fc193e
DOI: 10.1101/2024.11.07.622563

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting the Pathway Involvement of Compounds Annotated in the Reactome Knowledge-baseDOI 10.1101/2024.11.07.622563Read

Predicting the Pathway Involvement of Metabolites in Both Pathway Categories and Individual PathwaysSemantic proximity Read

Benchmark dataset for training machine learning models to predict the pathway involvement of metabolitesSemantic proximity Read

Pathway databases: making chemical and biological sense of the genomic data flood.Semantic proximity Read

Knowledge-Driven Interpretable Neural Networks for Mechanistic InsightSemantic proximity Read

Supervised learning techniques to predict compounds in pathway modules based on molecular propertiesSemantic proximity Read

Reactome pathway analysis to enrich biological discovery in proteomics data setsSemantic proximity Read

Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network.Semantic proximity Read

Using the Reactome DatabaseSemantic proximity Read

Viime-Path: An Interactive Metabolic Pathway Generation Tool for Metabolomics Data AnalysisSemantic proximity Read

datadrivenhypothesis.org: A resource for metabolic gene discovery through integrated pathway co-essentiality mappingSemantic proximity Read

BioHackJP 2023 Report R3: Expand the pathway analysis environment to non-model organismsSemantic proximity Read

Application of Large Language Models for Annotating Genes into Reactome PathwaysSemantic proximity Read