Article

Application of Large Language Models for Annotating Genes into Reactome Pathways

2025-12-23

Abstract excerpt

Reactome is the most comprehensive, open source, open access biological pathway knowledgebase, widely used in the research community. To ensure the highest quality of its content, human pathway data in Reactome is manually curated. However, manual curation is labor-intensive, time-consuming, and increasingly difficult to keep up with the ever-growing biomedical literature. Large language model (LLM)–driven artific...

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Literature Corpus work: 4285a98c-d178-5ca1-856b-46edbd38ad50
DOI: 10.64898/2025.12.20.695723

Open publication

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