Article

BRD1 haploinsufficiency disrupts neurodevelopmental and metabolic homeostasis in a translational minipig model

2025-10-22

Abstract excerpt

Psychiatric disorders are complex conditions characterized by substantial overlap in genetic risk and shared biological mechanisms. However, how individual risk genes contribute to shared disease mechanisms and disorder-specific phenotypes remains poorly understood. BRD1 has emerged as a chromatin-associated regulator with transdiagnostic relevance across psychiatric disorders and a central role in gene regulatory...

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Literature Corpus work: bbb7c4c3-af3e-5e02-a7a0-63b3159f98bb
DOI: 10.1101/2025.10.21.683618

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