Article

An organoid model of the menstrual cycle reveals the role of the luminal epithelium in regeneration of the human endometrium

2025-07-07

Abstract excerpt

Menstruation is an unusual physiological process whereby the human endometrium undergoes cyclical shedding yet scarless regeneration. Despite its pivotal role in reproductive health, the cellular states and interactions that coordinate this process are incompletely defined. Here, we establish an in vitro menstrual cycle (IVMC) protocol using human endometrial organoids that faithfully recapitulates the epithelium...

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Literature Corpus work: bbb17f7f-aa48-5256-bd6a-ae37dc5f72f0
DOI: 10.1101/2025.07.03.663000

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