Article

Mapping the temporal and spatial dynamics of the human endometrium <i>in vivo</i> and <i>in vitro</i>

2021-01-04

Abstract excerpt

The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout the menstrual cycle in response to ovarian hormones. We have generated single-cell and spatial reference maps of the human uterus and 3D endometrial organoid cultures. We dissect the signalling pathways that determine cell fate of the epithelial lineages in the lumenal and glandular microenvironments. Our benchmark of the endom...

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Literature Corpus work: 0d02f71e-2319-52c7-ab39-219d5f3f1130
DOI: 10.1101/2021.01.02.425073

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