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Glioma Pathophysiology: Insights Emerging from Proteomics

13 Jan 2010

Abstract excerpt

Proteomics is increasingly employed in both neurological and oncological research to provide insight into the molecular basis of disease but rarely has a coherent, novel pathophysiological insight emerged. Gliomas account for >50% of adult primary intracranial tumors, with malignant gliomas (anaplastic astrocytomas and glioblastoma multiforme) being the most common. In glioma, the application of proteomic...

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PMID: 20175778
DOI: 10.1111/j.1750-3639.2010.00376.x

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