Article
Clinical Characteristics and Magnetic Resonance Imaging-Based Prediction of the KLF4K409Q Mutation in Meningioma.
World neurosurgery - 1 Oct 2021
von Spreckelsen Niklas, Waldt Natalie, Timmer Marco, Goertz Lukas, Reinecke David, Laukamp Kai, Pennig Lenhard, Grau Stefan, Deckert Martina, Kirches Elmar, Stavrinou Pantelis, Mawrin Christian, Goldbrunner Roland
Abstract excerpt
BACKGROUND: Meningioma is the most common primary brain tumor in adults. In recent years, several non-neurofibromin 2 mutations, i.e., AKT1, SMO, TRAF7, and KLF4 mutations, specific for meningioma have been identified. This study aims to analyze the clinical impact and imaging characteristics of the KLF4K409Q mutation in meningioma. METHODS: Clinical, neuropathologic, and imaging data of 170 patients who...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.