Article

Predictive Evaluation of Quantitative Spatial Profiling of the Tumor Microenvironment by Multiplex Immunofluorescence in Recurrent Glioblastoma Treated with PD-1 Inhibitors

2021-06-01

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction: </bold>PD-1 inhibitors have shown limited efficacy in glioblastoma due to microenvironment immunosuppression and low tumor mutational burden. In GBM, PD-L1 expression is not a predictive marker for response to PD-1 or PD-L1 inhibitors. Multiplex immunostaining panel technology allows for detailed analyses of tumor microenvironment cells and their interaction. Our stu...

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Literature Corpus work: bbacabfc-e2d8-5859-8884-788e8d495819
DOI: 10.21203/rs.3.rs-341251/v2

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