Article
Comprehensive analysis of PD-L1 expression in glioblastoma multiforme.
Oncotarget - 27 Jun 2017
Heiland Dieter Henrik, Haaker Gerrit, Delev Daniel, Mercas Bianca, Masalha Waseem, Heynckes Sabrina, Gäbelein Annette, Pfeifer Dietmar, Carro Maria Stella, Weyerbrock Astrid, Prinz Marco, Schnell Oliver
Abstract excerpt
Glioblastoma multiforme are highly malignant brain tumours with frequent genetic and epigenetic alterations. The poor clinical outcome of these tumours necessitates the development of new treatment options. Immunotherapies for glioblastoma multiforme including PD1/PD-L1 inhibition are currently tested in ongoing clinical trials. The purpose of this study was to investigate the molecular background of PD-L1...
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