Article

SOX2 and NR2F1 coordinate the gene expression program of the early postnatal visual thalamus

2023-11-27

Abstract excerpt

The thalamic dorsolateral geniculate nucleus, (dLGN) receives visual input from the retina via the optic nerve, and projects to the cortical visual area, where eye-derived signals are elaborated. The transcription factors SOX2 and NR2F1 are directly involved in the differentiation of dLGN neurons, based on mouse work and patient mutations leading to vision defects. However, whether they regulate each other, or con...

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Literature Corpus work: bba083a2-ffcb-5edf-ae3a-83dd224c9f5b
DOI: 10.1101/2023.11.27.568801

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