Article

Mortality in hemodialysis: Synchrony of biomarker variability indicates a critical transition

2021-05-17

Abstract excerpt

Critical transition theory suggests that complex systems should experience increased temporal variability just before abrupt change, such as increases in clinical biomarker variability before mortality. We tested this in the context of hemodialysis using 11 clinical biomarkers measured every two weeks in 763 patients over 2496 patient-years. We show that variability – measured by coefficients of variation – is mor...

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Literature Corpus work: bb2b12d4-8176-5d36-b162-9b66a8cb1c17
DOI: 10.1101/2021.05.14.21257235

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