Article

Pan-cancer copy number variant analysis identifies optimized size thresholds and co-occurrence models for individualized risk-stratification

2024-01-11

Abstract excerpt

<title>Abstract</title> <p>Chromosome instability leading to accumulation of copy number gains or losses is a hallmark of cancer. Copy number variant (CNV) signatures are increasingly used for clinical risk-stratification, but size thresholds for defining CNVs are variable and the biological or clinical implications of CNV size heterogeneity or co-occurrence patterns are incompletely understood. Here we analyze C...

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Literature Corpus work: bb19f25e-b150-5e3d-9c22-4878acc678f6
DOI: 10.21203/rs.3.rs-3443805/v1

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