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Reciprocal F1 hybrids of two inbred mouse strains reveal parent-of-origin and perinatal diet effects on behavior and expression

2018-02-10

Abstract excerpt

<h4>ABSTRACT</h4> Parent-of-origin effects (POEs) in mammals typically arise from maternal effects or from imprinting. Mutations in imprinted genes have been associated with psychiatric disorders, as well as with changes in a handful of animal behaviors. Nonetheless, POEs on complex traits such as behavior remain largely uncharacterized. Furthermore, although perinatal environmental exposures, such as nutrient de...

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Literature Corpus work
bad13a1e-794a-5bd7-bbc2-e9665bec23ee
DOI
10.1101/262642
Open publication

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Reciprocal F1 hybrids of two inbred mouse strains reveal parent-of-origin and perinatal diet effects on behavior and expressionDOI 10.1101/262642
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