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Precise MRI-Histology Coregistration of Paraffin-Embedded Tissue with Blockface Imaging

2025-06-05

Abstract excerpt

Magnetic resonance imaging (MRI) provides 3D spatial information on tissue, yet it lacks at the molecular level. In contrast, histology provides cellular and molecular information, but it lacks the 3D spatial context and direct in vivo translation. Coregistering the two is key for the 3D-embedding of histological details, validating pathological MRI findings, and finding quantitative imaging biomarkers of neurode...

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Literature Corpus work
ba2ba00d-38b4-5dac-8213-7f8119b2b7e4
DOI
10.1101/2025.06.02.657335
Open publication

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Precise MRI-Histology Coregistration of Paraffin-Embedded Tissue with Blockface ImagingDOI 10.1101/2025.06.02.657335
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