Article

A prognostic signature for lung adenocarcinoma in people who have never smoked

2025-08-16

Abstract excerpt

Knowledge of tumor cell dynamics can inform prognosis and treatment yet is largely lacking for lung adenocarcinoma in people who have never smoked (NS-LUAD). With RNA-seq data from 684 NS-LUAD and validation in an independent dataset, we identified three subtypes with distinct phenotypic traits and cell compositions. Additional genomic and histological data further characterized the subtypes. ‘Steady’ , marked by...

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Literature Corpus work: ba277e16-3abf-524e-a8e8-709455b75d2e
DOI: 10.1101/2025.08.13.670169

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