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DNA capture and amplicon enrichment approaches for next-generation sequencing of <i>Mycoplasma genitalium</i> directly from clinical samples

2026-05-01

Abstract excerpt

Direct genome sequencing of Mycoplasma genitalium from clinical specimens is challenging due to the organism’s low bacterial load. We developed and compared two DNA enrichment strategies—amplicon-based and hybridisation capture-based—coupled with next-generation sequencing, and assessed the suitability of DNA capture for whole-genome sequencing and high-resolution molecular typing. The enrichment approaches, RNA...

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Literature Corpus work
ba05274d-3ea4-5ceb-aede-0852a2c0144c
DOI
10.64898/2026.04.29.26351683
Open publication

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DNA capture and amplicon enrichment approaches for next-generation sequencing of <i>Mycoplasma genitalium</i> directly from clinical samplesDOI 10.64898/2026.04.29.26351683
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