Article
A lipid-structured model for macrophage populations in atherosclerotic plaques
2019-02-22
Abstract excerpt
Atherosclerosis is a chronic inflammatory disease driven by the accumulation of pro-inflammatory, lipid-loaded macrophages at sites inside artery walls. These accumulations lead to the development of atherosclerotic plaques. The rupture of plaques that contain lipid-rich necrotic cores can trigger heart attacks and strokes via occlusion of blood vessels. We construct and analyse a system of partial integro-differe...
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Identifiers and source
- Literature Corpus work
- b9ba3788-9f06-50b7-a98f-0e319e9b9585
- DOI
- 10.1101/557538