Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blood Lipoproteins Shape the Phenotype and Lipid Content of Early Atherosclerotic Lesion Macrophages: A Dual-Structured Mathematical Model.

Bulletin of mathematical biology - 2 Aug 2024

Chambers Keith L, Myerscough Mary R, Watson Michael G, Byrne Helen M

Abstract excerpt

Macrophages in atherosclerotic lesions exhibit a spectrum of behaviours or phenotypes. The phenotypic distribution of monocyte-derived macrophages (MDMs), its correlation with MDM lipid content, and relation to blood lipoprotein densities are not well understood. Of particular interest is the balance between low density lipoproteins (LDL) and high density lipoproteins (HDL), which carry bad and good cholesterol...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Lipoproteins, HDL

Share to Lipoproteins, LDL

Share to Macrophages

Share to Mathematical Concepts

Share to Models, Cardiovascular

Source

Open in PubMed Open full text

Identifiers

PMID: 39093509
DOI: 10.1007/s11538-024-01342-9
PMCID: PMC11297092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blood Lipoproteins Shape the Phenotype and Lipid Content of Early Atherosclerotic Lesion Macrophages: A Dual-Structured Mathematical Model.PMID 39093509Read ↗

A lipid-structured model for macrophage populations in atherosclerotic plaquesSemantic proximity Read ↗

Modelling the continuum of macrophage phenotypes and their role in inflammation.Semantic proximity Read ↗

Deciphering Macrophage Phenotypes upon Lipid Uptake and AtherosclerosisSemantic proximity Read ↗

A Mathematical Model for Smooth Muscle Cell Phenotype Switching In Atherosclerotic Plaque.Semantic proximity Read ↗

Macrophage Plasticity and Atherosclerosis TherapySemantic proximity Read ↗

Macrophage heterogeneity in atherosclerosis: A matter of context.Semantic proximity Read ↗

A Review of Macrophage Diversity and Immune Checkpoint Regulation in Atherosclerosis: Insights from Single-Cell TranscriptomesSemantic proximity Read ↗

Macrophage Phenotype and Function in Different Stages of Atherosclerosis.Semantic proximity Read ↗

Macrophage Diversity and Polarization in AtherosclerosisSemantic proximity Read ↗

Functional Phenotypes of Intraplaque Macrophages and Their Distinct Roles in Atherosclerosis Development and AtheroinflammationSemantic proximity Read ↗

A novel strategy to dissect multifaceted macrophage function in human diseasesSemantic proximity Read ↗

Integrating the characteristic genes of macrophage pseudotime analysis in single-cell RNA-seq to construct a prediction model of atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.