Article

Revisiting the cancer microbiome using PRISM

2025-01-24

Abstract excerpt

Recent controversy around the cancer microbiome highlights the need for improved microbial analysis methods for human genomics data. We developed PRISM, a computational approach for precise microorganism identification and decontamination from low-biomass sequencing data. PRISM removes spurious signals and achieves excellent performance when benchmarked on a curated dataset of 62,006 known true- and false-positive...

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Literature Corpus work: b9af3f78-e0da-52f2-9b3d-c43ce10c1fff
DOI: 10.1101/2025.01.21.634087

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