Article

Tumor-microbiome links subtype, cellular programs, and immunity in pancreatic cancer

2021-10-01

Abstract excerpt

<title>Abstract</title> <p>Microorganisms are detected in multiple cancer types, including in putatively sterile organs, but it is unclear whether this relates to specific tissue contexts and influences oncogenesis or anti-tumor responses in humans. We developed SAHMI, a framework to analyze host-microbiome interactions using single-cell sequencing data. Interrogating pancreatic ductal adenocarcinomas (PDA), we i...

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Literature Corpus work: dc1b1399-25df-5363-aa65-826fcb1f79a9
DOI: 10.21203/rs.3.rs-929279/v1

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