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Article

Biodiversity and biogeography of the multi-kingdom cancer microbiome.

Cell - 11 Jun 2026

Dohlman Anders B, Mjelle Robin, Wood Henry M, Jiang Kevin, Shumate Alaina, Lee Iris, Piccinno Gianmarco, Serna Garazi, Yakubu Abdul-Rakeem, Nuciforo Paolo, Quirke Phil, Huttenhower Curtis, Segata Nicola, Meyerson Matthew

Abstract excerpt

Microorganisms represent an important component of the tumor microenvironment, but conflicting reports have left the extent of microbial prevalence across cancer types unclear, necessitating more robust methods for characterizing tumor-associated microbiomes. We built and benchmarked a host-subtraction and classification pipeline to identify microbiota in whole-genome sequencing data and applied it to 16,369...

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Identifiers

PMID: 42092351
DOI: 10.1016/j.cell.2026.04.015
PMCID: PMC13160245

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