Article

Melatonin Alleviates Chronic Intermittent Hypoxia-induced Microbiota Dysbiosis and Attenuates Intestinal Barrier Dysfunction via STAT3/Th17 signalling pathway

2023-03-24

Abstract excerpt

<h4>Background: </h4> Chronic intermittent hypoxia (CIH) triggers subclinical intestinal barrier disruption prior to systemic low-grade inflammation. Increasing evidence suggests therapeutic effects of melatonin on systemic inflammation and gut microbiota remodelling. However, whether and how melatonin alleviates CIH-induced intestinal barrier dysfunction remains unclear. <h4>Methods: </h4>: C57BL/6J mice and Caco...

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Literature Corpus work: b989627a-4681-5f27-b5e4-ebc3a261cd9c
DOI: 10.21203/rs.3.rs-2715995/v1

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