Article
The role of B cells in immune cell activation in polycystic ovary syndrome
2023-01-27
Abstract excerpt
Variations in B cell numbers are associated with polycystic ovary syndrome (PCOS) through unknown mechanisms. Here we demonstrate that B cells are not central mediators of PCOS pathology and that their frequencies are altered as a direct effect of androgen receptor activation. Hyperandrogenic women with PCOS have increased frequencies of age-associated double-negative B memory cells and increased levels of circula...
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Identifiers and source
- Literature Corpus work
- b96cbb8e-56dc-5e17-acde-f405a35c4f2f
- DOI
- 10.1101/2023.01.26.525671