High-fat Diet Alters Male Seminal Plasma Composition to Impair Female Immune Adaptation for Pregnancy in Mice.

doi:10.1210/endocr/bqab123

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Article

High-fat Diet Alters Male Seminal Plasma Composition to Impair Female Immune Adaptation for Pregnancy in Mice.

Endocrinology - 1 Oct 2021

Schjenken John E, Moldenhauer Lachlan M, Sharkey David J, Chan Hon Y, Chin Peck Y, Fullston Tod, McPherson Nicole O, Robertson Sarah A

Abstract excerpt

Paternal experiences and exposures before conception can influence fetal development and offspring phenotype. The composition of seminal plasma contributes to paternal programming effects through modulating the female reproductive tract immune response after mating. To investigate whether paternal obesity affects seminal plasma immune-regulatory activity, C57Bl/6 male mice were fed an obesogenic high-fat diet...

Topics

Adiposity
Animals
Body Composition
Cytokines
Diet, High-Fat
Female
Lymphocyte Subsets
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Phenotype

Plasma

Pregnancy

Pregnancy, Animal

Protein Isoforms

Reproduction

Source

Open in PubMed

Identifiers

PMID: 34170298
DOI: 10.1210/endocr/bqab123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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