Article
Modelling human glomerulosclerosis in vitro
2021-01-01
Abstract excerpt
Glomerulosclerosis is a feature of many chronic kidney diseases. Glomeruli are composed of glomerular endothelial cells (GECs), podocytes (PODs) and mesangial cells (MCs), and dysregulation in the interaction between these cell types results in glomerulosclerosis. This is characterised by excessive extracellular matrix deposition and cell dysfunction leading to disproportionate MC proliferation and POD loss. Anima...
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Identifiers and source
- Literature Corpus work
- b90cc435-af09-5fa4-b49f-2d4d8515a479
- DOI
- 10.17863/cam.71703