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HIV-1 Suppresses Notch-1 Expression in HPV-16+ CaSki Cells for Cancer Progression

2021-05-12

Abstract excerpt

<h4>Background: </h4> High Risk Human Papilloma Viruses (HR-HPV) recurrently infect women having Human Immunodeficiency Virus − 1 (HIV-1)infection. Transforming HPV E6 and E7 genes promote invasive cancers and interact with Notch-1receptor. Concomitantly, HIV-1 Tat binds to EGF motifs within the Notch-1extracellular domain. HR-HPV infection activates Notch-1 signalling. Permissive HIV-1entry into the cervix is all...

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Literature Corpus work
b8e5e556-2ef6-5eb5-9f39-4c84017c807f
DOI
10.21203/rs.3.rs-497573/v1
Open publication

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HIV-1 Suppresses Notch-1 Expression in HPV-16+ CaSki Cells for Cancer ProgressionDOI 10.21203/rs.3.rs-497573/v1
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