Article

Molecular biology of colorectal cancer: Review of the literature

2013-01-01

Abstract excerpt

Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic epithelium to colon adenocarcinoma. From the analysis of the molecular genesis of colon cancer, four central tenets concerning the pathogenesis of cancer have been established. The first is that the genetic and epigenetic alterations that underlie colon cancer fo...

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Literature Corpus work: b8d3a24c-8b8f-5eb6-9cee-10665a3979f0
DOI: 10.4236/ajmb.2013.32010

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