Article
Molecular pathogenesis of colorectal cancer: implications for molecular diagnosis.
Cancer - 15 Nov 2005
Arnold Christian N, Goel Ajay, Blum Hubert E, Boland C Richard
Abstract excerpt
Colorectal cancer is the third leading cause of cancer-related death in both men and woman in industrialized countries. Major advances have been made in our understanding of molecular events leading to formation of adenomatous polyps and cancer. Most colorectal cancers are sporadic, but a significant proportion (5-6%) has a clear genetic background. It is now widely accepted that colorectal carcinogenesis is a...
Topics
- Colorectal Neoplasms
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Mass Screening