Article

EDA-E7 activated DCs induces specific cytotoxic T lymphocyte immune responses against HPV expressing cervical cancer in human setting

2022-07-19

Abstract excerpt

<title>Abstract</title> <p>Background Cervical cancer is a major cause of cancer death in women worldwide. Human papillomavirus (HPV) infection especially genotypes 16 and 18 is the main factor induces cervical lesions. Targeting HPV viral oncoproteins E6 and E7 is a new strategy for cervical cancer immunotherapy and has been associated with resolution of HPV-induced lesions. How to efficiently induce T cell tar...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9d5121e2-3711-56da-bef8-4e0c23045cb7
DOI: 10.21203/rs.3.rs-1782711/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

EDA-E7 activated DCs induces specific cytotoxic T lymphocyte immune responses against HPV expressing cervical cancer in human settingDOI 10.21203/rs.3.rs-1782711/v1Read

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigensSemantic proximity Read

Human Papillomavirus E6 and E7: The Cervical Cancer Hallmarks and Targets for TherapySemantic proximity Read

DNA vaccines for cervical cancer: from bench to bedsideSemantic proximity Read

Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategiesSemantic proximity Read

E6 and E7 Oncoproteins: Potential Targets of Cervical CancerSemantic proximity Read

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancerSemantic proximity Read

A Promising New Model: Establishment of Patient‐Derived Organoid Models Covering HPV‐Related Cervical Pre‐Cancerous Lesions and Their CancersSemantic proximity Read

Impaired HPV driven CD8 T cells recognition and Immune suppression in HPV-Induced Cervical CancerSemantic proximity Read

Design of a multi-epitope vaccine against cervical cancer using immunoinformatics approachesSemantic proximity Read

The Role of HPV E6 and E7 Oncoproteins in HPV-associated Cervical CarcinogenesisSemantic proximity Read

Delivery of genome editing tools: A promising strategy for HPV-related cervical malignancy therapySemantic proximity Read