Article

Whole-genome benchmarking reveals context-specific error rates in the Ultima UG100 and Illumina NovaSeqX Platforms

2026-03-02

Abstract excerpt

Whole genome sequencing (WGS) is becoming more common in research and clinical applications, but there is a paucity of comparative data between high-throughput WGS platforms. We benchmarked the Ultima Genomics UG100 system against Illumina NovaSeqX using the Genome in a Bottle (GIAB) WGS reference set sample HG002. Across NIST v4.2.1 benchmark regions, UG100 exhibited higher total variant-calling errors (27x), pri...

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Literature Corpus work: b84ba943-5cae-526d-bb28-80a341676ee9
DOI: 10.64898/2026.02.27.708547

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