Article

Short-Read Sequencing Benchmarking with Donor-Specific Assemblies

2026-06-28

Abstract excerpt

<h4>Background</h4> High-throughput short-read sequencing has become a core technology for genomics, but the rapid expansion of available platforms has made it increasingly important to benchmark them under standardized conditions. A major challenge is that conventional reference-based comparisons confound true sequencing errors with inherited variation and reference bias, making it difficult to isolate platform-...

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Literature Corpus work: 47614f40-d969-52e1-ae0a-7b11d25e2110
DOI: 10.64898/2026.06.24.734333

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