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An 8-Gene Bevacizumab Resistance Signature Predicts Prognosis and Reveals Immunosuppressive Microenvironment in Colorectal Cancer

2026-05-20

Abstract excerpt

<h4>Background</h4> Bevacizumab resistance severely limits long-term efficacy in metastatic colorectal cancer (CRC). This study aimed to develop and validate a bevacizumab resistance-associated gene signature for prognosis prediction and immune microenvironment characterization in CRC. <h4>Methods</h4> Two GEO datasets (GSE19862, GSE86582) with bevacizumab response data and TCGA-COAD/READ RNA-seq data were analy...

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Literature Corpus work
b8310daa-2665-50eb-8c11-d8b776a99080
DOI
10.64898/2026.05.17.725749
Open publication

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An 8-Gene Bevacizumab Resistance Signature Predicts Prognosis and Reveals Immunosuppressive Microenvironment in Colorectal CancerDOI 10.64898/2026.05.17.725749
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