Article

Hypoxia-related Genes as Prognostic Signature to Predict Prognosis and Immune Microenvironment of Colorectal Cancer Patients

2021-02-23

Abstract excerpt

<h4>Background: </h4> Hypoxia is widespread in solid tumors and is directly associated with colorectal cancer (CRC) aggressiveness, poor prognosis, and immunotherapy resistance. In this study, we aimed at developing a hypoxia-related marker to improve the prognosis prediction in CRC. <h4>Methods:</h4> We used gene expression data of CRC samples from the Cancer Genome Atlas Database and the hypoxia gene set to obta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 38033d64-7a6b-54fc-8f73-c627b206c4f3
DOI: 10.21203/rs.3.rs-219462/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hypoxia-related Genes as Prognostic Signature to Predict Prognosis and Immune Microenvironment of Colorectal Cancer PatientsDOI 10.21203/rs.3.rs-219462/v1Read

Development of a novel hypoxia-immune–related LncRNA risk signature for predicting the prognosis and immunotherapy response of colorectal cancerSemantic proximity Read

Identification of a Hypoxia-Related LncRNA Signature for the Prognosis of Colorectal CancerSemantic proximity Read

Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor MicroenvironmentSemantic proximity Read

Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancerSemantic proximity Read

Identification of prognostic immune‐related gene signature associated with tumor microenvironment of colorectal cancerSemantic proximity Read

Identification of a hypoxia-related gene prognostic signature in colorectal cancer based on bulk and single-cell RNA-seqSemantic proximity Read

Development of a metastasis-related genes prognostic model for colorectal cancerSemantic proximity Read

Identification and Validation of A Hypoxia-Related Prognostic and Immune Microenvironment Signature in Bladder CancerSemantic proximity Read

Characterization of an endoplasmic reticulum stress-related signature to predict prognosis in Colorectal AdenocarcinomaSemantic proximity Read

Identification and validation of a hypoxia-related prognostic and immune microenvironment signature in bladder cancerSemantic proximity Read

Constructing Tumor Immune Microenvironment and Identifying the Immune-Related Prognostic Signatures in Colorectal Cancer Using Multi-omics DataSemantic proximity Read