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Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite

2024-08-28

Abstract excerpt

<h4>Summary</h4> Genome organization plays a significant role in silencing heterochromatinized genes in the most virulent human malaria parasite, Plasmodium falciparum . However, it remains unclear how heterochromatinized genes spatially cluster or if active genes are also organized in a specific manner. We used Micro-C to achieve a near-nucleosome resolution DNA-DNA contact map, which revealed new inter- and in...

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Literature Corpus work
b8269aab-9f0d-54f5-810a-80a8659a9230
DOI
10.1101/2024.08.28.610079
Open publication

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Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasiteDOI 10.1101/2024.08.28.610079
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