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The ApiAP2 factor PfAP2-HC is an integral component of heterochromatin in the malaria parasite Plasmodium falciparum

19 Apr 2021

Abstract excerpt

Malaria parasites undergo a complex life cycle in the human host and the mosquito vector. The ApiAP2 family of DNA-binding proteins plays a dominant role in parasite development and life cycle progression. Most ApiAP2 factors studied to date act as transcription factors regulating stage-specific gene expression. Here, we characterized an ApiAP2 factor in Plasmodium falciparum that we termed PfAP2-HC. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33997710
DOI: 10.1016/j.isci.2021.102444

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