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Computational Modeling of the Gut Microbiota Predicts Metabolic Mechanisms of Recurrent <i>Clostridioides difficile</i> Infection

2020-04-12

Abstract excerpt

Approximately 30% of patients who have a Clostridioides difficile infection (CDI) will suffer at least one incident of reinfection. While the underlying causes of CDI recurrence are poorly understood, interactions between C. difficile and other commensal gut bacteria are thought to play an important role. In this study, an in silico metagenomics pipeline was used to process taxa abundance data from 225 CDI pati...

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Literature Corpus work
b7ee99d8-c5cf-5996-b509-be17d5cc12a8
DOI
10.1101/2020.04.10.036111
Open publication

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Computational Modeling of the Gut Microbiota Predicts Metabolic Mechanisms of Recurrent <i>Clostridioides difficile</i> InfectionDOI 10.1101/2020.04.10.036111
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