Article

The use of first polar bodies for preimplantation diagnosis of aneuploidy

1995-01-01

Abstract excerpt

A large proportion of patients undergoing in-vitro fertilization (IVF) are aged ≥35 years. It has been estimated that in this age group, 50% of embryos are chromosomally abnormal, with aneuploidy being the major contributing factor. Since the origin of most aneuploidies is maternal meiosis I non-disjunction, unfertilized oocytes could be safely screened for aneuploidy by analysing their first polar bodies. To dete...

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Literature Corpus work: b7da870f-7d0b-5842-9591-efef112f5c54
DOI: 10.1093/molehr/1.2.94

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