Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Meiotic and mitotic nondisjunction: lessons from preimplantation genetic diagnosis

19 Aug 2004

Abstract excerpt

Direct testing of the outcome of the first and second meiotic divisions has become possible with the introduction of preimplantation genetic diagnosis (PGD) for aneuploidies. Testing of oocytes by fluorescent in situ hybridization (FISH) analysis of the first and second polar bodies showed that more than half of oocytes from the IVF patients aged 35 years and older had chromosomal abnormalities, which originated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15319376
DOI: 10.1093/humupd/dmh036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meiotic and mitotic nondisjunction: lessons from preimplantation genetic diagnosisPMID 15319376Read ↗

The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidySemantic proximity Read ↗

Chromosome Abnormalities in the Human OocyteSemantic proximity Read ↗

Chromosomal Aberrations as a Biological Phenomenon in Human Embryonic DevelopmentSemantic proximity Read ↗

Diagnosing and preventing inherited disease: The use of first polar bodies for preimplantation diagnosis of aneuploidySemantic proximity Read ↗

Delivery of a chromosomally normal child from an oocyte with reciprocal aneuploid polar bodies.Semantic proximity Read ↗

Aneuploidy in oocytes from women of advanced maternal age: analysis of the causal meiotic errors and impact on embryo developmentSemantic proximity Read ↗

Frequency and distribution of chromosome abnormalities in human oocytesSemantic proximity Read ↗

Human oocytes harbouring damaged dna can complete meiosis-iSemantic proximity Read ↗

On the origins and fate of chromosomal abnormalities in human preimplantation embryos: an unsolved riddleSemantic proximity Read ↗

Increased susceptibility to maternal aneuploidy demonstrated by comparative genomic hybridization analysis of human MII oocytes and first polar bodies.Semantic proximity Read ↗

Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryosSemantic proximity Read ↗

Errors of the Egg: The Establishment and Progression of Human Aneuploidy Research in the Maternal GermlineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.