Article
Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 2008
Chiu Ting-Lan, Wen Zhimou, Rupasinghe Sanjeewa G, Schuler Mary A
Abstract excerpt
One of the challenges faced in malarial control is the acquisition of insecticide resistance that has developed in mosquitoes that are vectors for this disease. Anopheles gambiae, which has been the major mosquito vector of the malaria parasite Plasmodium falciparum in Africa, has over the years developed resistance to insecticides including dieldrin, 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane (DDT), and...
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