Article

The impact of consanguinity on human health and disease with an emphasis on rare diseases

2022-12-07

Abstract excerpt

Abstract Purpose Consanguinity increases the likelihood of the inheritance of homozygous pathogenic alleles which may predispose to rare autosomal recessive disorders. Here we discuss the role of consanguinity in informing inherited disease with a focus on rare diseases. Methods We reviewed the literature concerning the impact of consanguinity on human diseases and chose examples to illustrate the most important t...

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Literature Corpus work: b6f27536-0da8-55da-9449-217822e14ecc
DOI: 10.1007/s44162-022-00004-5

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