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Reduction in mRNA expression of the neutrophil chemoattract factor CXCL1 in <i>Pseudomonas aeruginosa</i> treated Barth Syndrome B lymphoblasts

2023-04-18

Abstract excerpt

Barth Syndrome (BTHS) is a rare X-linked genetic disease caused by a mutation in TAFAZZIN , a cardiolipin transacylase. Approximately 70% of patients with BTHS exhibit severe infections due to neutropenia. However, neutrophils from BTHS patients have been shown to exhibit normal phagocytosis and killing activity. B lymphocytes play a crucial role in the regulation of the immune system and when activated secret cy...

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Literature Corpus work
b6ba16e8-0bf4-59cd-b339-723eebde2b73
DOI
10.1101/2023.04.18.537385
Open publication

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Reduction in mRNA expression of the neutrophil chemoattract factor CXCL1 in <i>Pseudomonas aeruginosa</i> treated Barth Syndrome B lymphoblastsDOI 10.1101/2023.04.18.537385
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