Article

Evaluating the analytical validity of mutation calling pipeline for tumor whole exome sequencing

2022-11-18

Abstract excerpt

Detecting somatic mutations from the patients’ tumor tissues has the clinical impacts in medical decision making. Library preparation methods, sequencing platforms, read alignment tools and variant calling algorithms are the major factors to influence the data analysis results. Understanding the performance of the tool combinations of the somatic variant calling pipelines has become an important issue in the use o...

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Literature Corpus work: b6a322f4-8a6f-5706-b229-2657cdcaea74
DOI: 10.1101/2022.11.17.516840

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