Article

Optimal transport reveals dynamic gene regulatory networks via gene velocity estimation

2024-09-16

Abstract excerpt

Inferring gene regulatory networks from gene expression data is an important and challenging problem in the biology community. We propose OTVelo, a methodology that takes time-stamped single-cell gene expression data as input and predicts gene regulation across two time points. It is known that the rate of change of gene expression, which we will refer to as gene velocity, provides crucial information that enhance...

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Literature Corpus work: b6a074d6-6912-575d-9151-2a6499ec3e30
DOI: 10.1101/2024.09.12.612590

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