Article

An integrated analysis of the structural changes and gene expression of spleen in human visceral leishmaniasis with and without HIV coinfection

2023-12-22

Abstract excerpt

The spleen plays a pivotal role in the pathogenesis of visceral leishmaniasis. In severe forms of the disease, the spleen undergoes changes that can compromise its function in surveilling blood-circulating pathogens. In this study, we present an integrated analysis of the structural and gene expression alterations in the spleens of three patients with relapsing visceral leishmaniasis, two of whom were coinfected w...

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Literature Corpus work: b671ed72-42f0-50c2-843a-8d42373a9f3a
DOI: 10.1101/2023.12.21.572737

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